The Chesapeake Society of Gastroenterology Nurses and Associates
The Chesapeake Society of Gastroenterology Nurses and Associates is affiliated with the National Society of Gastroenterology Nurses and Associates (SGNA). CSGNA is a group of professional nurses and associates of various backgrounds whose goal is to provide optimal care to patients seeking treatment for gastrointestinal disorders. Gastrointestinal (GI) Nurses and Associates practice in hospitals, ambulatory endoscopy centers, and physician offices. We strive to enhance our own clinical knowledge through educational programs incorporating new concepts in an ever-changing technology.
The CSGNA is looking for enthusiastic members in making our Society the best that it can be.
Latest GI News
- Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome AnalysesIt has been a challenge to develop fully functioning cells from human pluripotent stem cells (hPSCs). We investigated how activation of hedgehog signaling regulates derivation of enteric neural crest (NC) cells from hPSCs. ... read more
- Can Retrospective Studies Confirm Causes of Drug-Induced Liver Injury?Because of the significant academic influence of Gastroenterology, the article Incidence and Etiology of Drug-Induced Liver Injury in Mainland China has caused great impact in mainland China.1 We appreciate the dedication of Professor Mao Yimin and his team to drug-induced liver injury (DILI) research. However, there are several deficiencies in the study design and the research conclusion might be arbitrary. Those deficiencies could trigger readers’ to have misunderstand the incidence ... read more
- Eradication of Helicobacter pylori in Children Restores the Structure of the Gastric Bacterial Community to That of Noninfected ChildrenHelicobacter pylori alters the gastric microbial composition and causes reduced gastric inflammatory disease in children in Chile.1–3 These findings suggest that H pylori–associated gastric microbiota may influence the pathogenesis of H pylori infection beginning in childhood, at least in Chile. Here we characterized the gastric microbiota in H pylori–infected children in an entirely different geographic region of South America, namely Venezuela, where H pylori also is endemic,4 and determined the ... read more
- Neonatal Life Events and the Risk of Inflammatory Bowel DiseaseWe read with interest the report of Bernstein et al1 about early life events affecting the risk of later development of inflammatory bowel disease (IBD). Early life exposures are thought to modulate the risk for IBD and understanding disease risk-modulating events is quintessential to the efforts of preventing IBD. Therefore, we welcome this epidemiologic study and its contribution to the understanding of this important stage in the life of patients with ... read more
- Events Early in Life, But Not the Neonatal Period, Affect Risk for Later Development of Inflammatory Bowel DiseaseI read with great interest the article by Bernstein et al1 examining early life events and the subsequent risk of developing inflammatory bowel disease (IBD). The authors used a wide range of models to determine those events that occur early in life and their influence on the subsequent development of IBD. One area that was not looked at was siblings with IBD. Siblings share a genetic similarity to each other that ... read more
- The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in MiceThe histone lysine demethylase 3A (KDM3A) demethylates H3K9me1 and H3K9Me2 to increase gene transcription and is upregulated in tumors, including pancreatic tumors. We investigated its activities in pancreatic cancer cell lines and its regulation of the gene encoding doublecortin calmodulin-like kinase 1 (DCLK1), a marker of cancer stem cells. ... read more
- RE: Incidence and Etiology of Drug-Induced Liver Injury in Mainland ChinaWe read with great interest the article by Shen et al1 on the Incidence and Etiology of Drug-Induced Liver Injury in Mainland China. The number of cases suspected of drug-induced liver injury (DILI) reported (>25,900!) is impressive, and by far the largest number reported in any study on DILI so far. The article is generally well-written. However, there are several important issues that needs to be taken into consideration which makes ... read more
- Transgenic Expression of PRSS1R122H Sensitizes Mice to PancreatitisMutations in the trypsinogen gene (PRSS1) cause human hereditary pancreatitis. However, it is not clear how mutant forms of PRSS1 contribute to disease development. We studied the effects of expressing mutant forms of human PRSS1 in mice. ... read more
- Tumor Seeding During Colonoscopy as a Possible Cause for Metachronous Colorectal CancerIn patients who have undergone surgery for colorectal cancer (CRC), 3% have recurrence of (metachronous) CRC. We investigated whether tumor seeding during colonoscopy (iatrogenic implantation of tumor cells in damaged mucosa) increases risk for metachronous CRC. ... read more
- A Slow and Distended StomachQuestion: A 33-year-old woman presented with a 10-day history of painless jaundice. During this time, she also noted decreased appetite, malaise, and pruritus. On occasion, she would have heartburn and belching that would improve with an antacid. She denied any right upper quadrant pain and weight loss. She was not currently taking any medications, including acetaminophen. She had a past medical history of methamphetamine use in recent remission. She had ... read more