The Chesapeake Society of Gastroenterology Nurses and Associates
The Chesapeake Society of Gastroenterology Nurses and Associates is affiliated with the National Society of Gastroenterology Nurses and Associates (SGNA). CSGNA is a group of professional nurses and associates of various backgrounds whose goal is to provide optimal care to patients seeking treatment for gastrointestinal disorders. Gastrointestinal (GI) Nurses and Associates practice in hospitals, ambulatory endoscopy centers, and physician offices. We strive to enhance our own clinical knowledge through educational programs incorporating new concepts in an ever-changing technology.
The CSGNA is looking for enthusiastic members in making our Society the best that it can be.
Latest GI News
- Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular CarcinomasIntratumor heterogeneity and divergent clonal lineages within and among primary and recurrent hepatocellular carcinomas (HCCs) produce challenges to patient management. We investigated genetic and epigenetic variations within liver tumors, among hepatic lesions, and between primary and relapsing tumors. ... read more
- Plasticity of Th17 Cells Contributes to Crohn’s DiseaseWe read with great interest the recently published article titled “Correction of defective T regulatory cells from patients with Crohn's disease by ex vivo ligation of retinoic acid receptor α.” In this article, Goldberg et al1 reported that T regulatory cells (Treg) from patients with Crohn's disease (CD) exhibit lower integrin levels, that is, α4β7, than Treg from healthy controls. They further noted that in vitro treatment with retinoic acid receptor α (RARα) ... read more
- Adipose-Derived Therapeutic Products for the Management of Refractory Crohn’s FistulaWe have read with great interest the recent article of Dige et al1 published in Gastroenterology titled “Efficacy of injection of freshly collected autologous adipose tissue into perianal fistulas in patients with Crohn’s disease.” We would like to congratulate the authors of this article, who have performed a prospective interventional study reaching a rate of 57% of patients (12/21) with complete fistula healing 6 months after the last autologous adipose tissue ... read more
- Cost-Effectiveness and National Effects of Initiating Colorectal Cancer Screening for Average-Risk Persons at Age 45 Years Instead of 50 YearsWe very much appreciate the paper by Ladabaum et al1 presenting results from a Markov model to evaluate the cost-effectiveness of adopting the recent American Cancer Society recommendation to start colorectal cancer (CRC) screening for the average risk population at age 45; it adds a critical dimension to the discussion of the optimal age to start CRC screening. ... read more
- A Summary of Education Scholarship Presented at DDW 2019 and a Vision for the FutureThere is a tremendous amount of scholarship presented each year at Digestive Diseases Week (DDW). Medical education scholarship accounts for a small fraction of what is presented, and it differs from clinical and translational scholarship in important ways. Clinical and basic science scholarship tends to investigate more well-defined questions or topics within narrow disciplines and tends to report rigorous scientific observation after applying reproducible and validated methodologies. In contrast, educational ... read more
- Weight Loss and Granulomatous Liver DiseaseQuestion: A 33-year-old African-American woman without significant past medical history presented with 3 months’ of progressively worsening right upper quadrant abdominal pain. The pain was sharp, 10/10 severity, worsened during eating, and lasted ≤3 hours before resolving on its own. She also reported a 35- to 40-pound weight loss over the same period, which she attributed to low appetite in the setting of pain. The patient noted having nausea, but ... read more
- Report from the AGA Center for GI Innovation and Technology’s Consensus Conference: Envisioning Next-Generation Paradigms in Colorectal Cancer Screening and Surveillance... read more
- White-light Endoscopy is Adequate for Lynch Syndrome Surveillance in a Randomized and Non-inferiority StudyDye-based pancolonic chromoendoscopy is recommended for colorectal cancer surveillance in patients with Lynch syndrome. However, there is scarce evidence to support its superiority to high-definition white-light endoscopy. We performed a prospective study assess whether in the hands of high detecting colonoscopists, high-definition, white-light endoscopy is non-inferior to pancolonic chromoendoscopy for detection of adenomas in patients with Lynch syndrome. ... read more
- Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver DiseaseNonalcoholic fatty liver disease (NAFLD) has quickly become the most common chronic liver disease in children in many countries around the world.1–5 Estimates in Europe range from 1.3% to 22.5% of children being affected.2,6–9 In the United States, 9.6% of all children and 38.0% of obese adolescents are estimated to have NAFLD.10,11 In China, 45% of obese adolescents are estimated to have NAFLD.12 Certain populations have notable predisposition; for example, ... read more
- Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory CellsT-regulatory (Treg) cells suppress the immune response to maintain homeostasis. There are 2 main subsets of Treg cells: FOXP3 (forkhead box protein 3)-positive Treg cells, which do not produce high levels of effector cytokines, and type 1 Treg (Tr1) cells, which are FOXP3-negative and secrete interleukin (IL) 10. IL10 is an anti-inflammatory cytokine, so Tr1 cells might be used in the treatment of inflammatory bowel diseases. We aimed to develop ... read more